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Article

Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi

1 Nov 1995

Abstract excerpt

Previous studies have demonstrated that Borrelia burgdorferi in the midguts of infected ticks shows increased expression of the antigenic outer surface protein OspC after the ticks have ingested a blood meal. This differential expression is at least partly due to a change in temperature, as an increase in OspC levels is also observed when cultures are shifted from 23 to 35 degrees C. Immunoblotting of bacterial...

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PMID: 7591099
DOI: 10.1128/iai.63.11.4535-4539.1995

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