Protein ligands of the human adenovirus type 2 outer capsid identified by biopanning of a phage-displayed peptide library on separate domains of wild-type and mutant penton capsomers.

doi:10.1002/j.1460-2075.1995.tb00153.x

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Article

Protein ligands of the human adenovirus type 2 outer capsid identified by biopanning of a phage-displayed peptide library on separate domains of wild-type and mutant penton capsomers.

The EMBO journal - 2 Oct 1995

Hong S S, Boulanger P

Abstract excerpt

A filamentous phage-displayed random hexapeptide library was screened on the adenovirus type 2 (Ad2) penton capsomer and its separate domains, penton base, full-length fiber, fiber shaft and fiber knob. Affinity supports were designed to immobilize the penton ligate with a preferred orientation, via immuno-adsorption to pre-coated antibody. Three classes of phagotopes were distinguished in the eluates from the...

Topics

Adenoviruses, Human
Amino Acid Sequence
Antibodies, Monoclonal
Antibodies, Viral
Base Sequence
Capsid
Capsid Proteins
Cell Adhesion Molecules
Conserved Sequence
Fibronectins
HeLa Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunosorbent Techniques

Inovirus

Ligands

Molecular Sequence Data

Mutation

Oligopeptides

Source

Open in PubMed Open full text

Identifiers

PMID: 7588601
DOI: 10.1002/j.1460-2075.1995.tb00153.x
PMCID: PMC394569

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7588601-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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