Article
Immunoreactive domains and integrin-binding motifs in adenovirus penton base capsomer.
Viral immunology - 1 Jan 2000
Hong S S, Bardy M, Monteil M, Gay B, Denesvre C, Tournier J, Martin G, Eloit M, Boulanger P
Abstract excerpt
A panel of nine independent mouse monoclonal antibodies (MAbs) against penton base capsomers of subgenus C adenovirus serotypes 2 (Ad2) and 5 (Ad5) were isolated and characterized. Two of them (1D2 and 5A5), raised against Ad5 virion as the immunogen, bound to sodium dodecyl sulfate (SDS)-resistant and subgenus C-specific epitopes that were not present in subgenus B Ad3 penton base. The 1D2 and 5A5 epitopes were...
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