Article
Role of LPS length in clearance rate of bacteria from the bloodstream in mice.
Microbiology (Reading, England) - 1 Oct 1995
Ohno A, Isii Y, Tateda K, Matumoto T, Miyazaki S, Yokota S, Yamaguchi K
Abstract excerpt
Strains of Pseudomonas aeruginosa isolated from patients with cystic fibrosis (CF) never spread systemically. This may be due to serum sensitivity since these strains are very sensitive to complement-mediated bactericidal activity. A serum-resistant mutant, P. aeruginosa TUM3 HSR, was obtained from serum-sensitive strain TUM3 from a CF patient in order to clarify the mechanism of failure of systemic spread. LPS...
Topics
- Animals
- Blood Bactericidal Activity
- Blotting, Western
- Complement C3
- Lipopolysaccharides
- Liver
- Male
- Mice
- Mice, Inbred ICR
- Mutation
- O Antigens
- Phagocytosis