Article
The complex pathogenesis of bacteremia: from antimicrobial clearance mechanisms to the genetic background of the host.
Virulence - 1 Jan 2014
Christaki Eirini, Giamarellos-Bourboulis Evangelos J
Abstract excerpt
Bacteremia develops when bacteria manage to escape the host immune mechanisms or when the otherwise well-orchestrated immune response fails to control bacterial spread due to inherent or acquired immune defects that are associated with susceptibility to infection. The pathogenesis of bacteremia has some characteristic features that are influenced by the genetic signature of the host. In this review, the host...
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