Article
Protein-DNA interactions during phenotypic differentiation.
Molecular neurobiology - 1 Jan 1995
Dobi A L, Palkovits M, Palkovits C G, Santha E, van Agoston D
Abstract excerpt
We have been studying the molecular mechanism of neuronal differentiation through which the multipotent precursor becomes limited to the final transmitter phenotype. Here we focused on the role of the 5' proximal regulatory cassette (-190; +53 bp) of the rat enkephalin (rENK) gene in the developmental regulation of the enkephalin phenotype. Several well characterized cis-elements, including AP2, CREB, NF1, and...
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