Article
Development of midbrain and anterior hindbrain ocular motoneurons in normal and Wnt-1 knockout mice.
Journal of neurobiology - 1 Aug 1995
Fritzsch B, Nichols D H, Echelard Y, McMahon A P
Abstract excerpt
The effect of homozygotic Wnt-1-/- mutations on the development of ocular motoneurons was examined with the lipophilic dye DiI and compared to control and phenotypic wild-type mouse embryos. A piece of DiI-soaked filter paper was inserted into the orbit, the midbrain, or rhombomere 5 of the hindbrain in six paraformaldehyde-fixed litters (10.5, 12.5, and 14.5 days postcoitum) containing Wnt-1, Wnt+/-, and...
Topics
- Animals
- Carbocyanines
- Cranial Nerves
- Eye
- Fluorescent Dyes
- Homozygote
- Mesencephalon
- Mice
- Mice, Knockout
- Motor Neurons
- Neural Pathways
- Phenotype