Article
Population genetic study of the human dopamine transporter gene (DAT1).
Genetic epidemiology - 1 Jan 1995
Doucette-Stamm L A, Blakely D J, Tian J, Mockus S, Mao J I
Abstract excerpt
The human dopamine transporter gene, DAT1, acts to transport released dopamine into presynaptic terminals of the brain. The possibility that the DAT1 gene plays a role in genetic diseases of the brain has led to studies of DAT1 in several psychiatric and neurological disorders. Previous sequence analysis of DAT1 revealed a 40-bp repeat in the 3' end of the gene. In order to identify all potential alleles for this...
Topics
- Alleles
- Americas
- Black People
- Carrier Proteins
- DNA
- Dopamine
- Dopamine Plasma Membrane Transport Proteins
- Gene Frequency
- Hispanic or Latino
- Humans
- Membrane Glycoproteins
