Normal expression and the effects of ectopic expression of the Drosophila muscle segment homeobox (msh) gene suggest a role in differentiation and patterning of embryonic muscles.

Abstract excerpt

Myogenesis is a several step process that requires genes involved in specifying mesoderm lineage and genes involved in determining muscle identity, differentiation, and patterning. We report here on the isolation, characterization, and expression pattern of a cDNA clone encoded by the previously uncharacterized Drosophila muscle segment homeobox (msh) gene and its possible role in myogenesis. The amino acid...

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