Article
Pharmacological and genetic approaches for the study of circadian rhythms in mammals.
Frontiers in neuroendocrinology - 1 Jul 1995
Turek F W, Pinto L H, Vitaterna M H, Penev P D, Zee P C, Takahashi J S
Abstract excerpt
Two different approaches have been utilized to study the controlling mechanisms that underlie the generation and entrainment of circadian rhythms in mammals. The use of specific drugs to alter the period and/or the phase of circadian rhythms has provided new insights into both the pathways by which environmental information reaches the mammalian circadian pacemaker in the suprachiasmatic nuclei (SCN) and the...
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