Article
[Genetic analysis (PKD2) of autosomal dominant polycystic kidney disease].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - 1 Jan 2009
Gómez P Fraile, Moro E Corral, García-Cosmes P, Sarmiento R González, Romo J M Tabernero
Abstract excerpt
Autosomal dominant polycystic kidney disease is a multi-organic hereditary disorder. It is responsible for 7-10% of cases of end stage renal failure. It is caused by mutations in the genes PKD1 and PKD2. Both polycystic kidney disease's forms have a pathogeny and similar clinic, but in the patients with mutation in PKD2, the clinical manifestations appear later and the progression to end stage renal failure...
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