Ganglion cell axon pathfinding in the retina and optic nerve.

doi:10.1016/j.semcdb.2003.09.006

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Article

Ganglion cell axon pathfinding in the retina and optic nerve.

Seminars in cell & developmental biology - 1 Feb 2004

Oster S F, Deiner M, Birgbauer E, Sretavan D W

Abstract excerpt

The eye is a highly specialized structure that gathers and converts light information into neuronal signals. These signals are relayed along axons of retinal ganglion cells (RGCs) to visual centers in the brain for processing. In this review, we discuss the pathfinding tasks RGC axons face during development and the molecular mechanisms known to be involved. The data at hand support the presence of multiple axon...

Topics

Animals
Axons
Cell Differentiation
Cytoskeleton
Ephrins
Gene Expression Regulation, Developmental
Genes, Immunoglobulin
Growth Cones
Humans
Models, Biological
Mutation
Nerve Growth Factors
Nerve Tissue Proteins
Netrin-1
Optic Disk
Optic Nerve
Receptor, Insulin
Receptors, Eph Family

Source

Open in PubMed

Identifiers

PMID: 15036215
DOI: 10.1016/j.semcdb.2003.09.006

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