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Article

Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster.

Mechanisms of development - 1 Jun 1995

Raeber A J, Muramoto T, Kornberg T B, Prusiner S B

Abstract excerpt

To evaluate the fruit fly as a model for studying neurodegenerative diseases caused by prions, transgenic flies were generated by introducing the Syrian hamster prion protein (SHaPrP) gene into the Drosophila melanogaster germ line by P element-mediated transformation. Nine transgenic lines were isolated; induction of transgenes that had been placed under the control of the Drosophila heat shock promoter, hsp 70,...

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PMID: 7547477
DOI: 10.1016/0925-4773(95)00379-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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