Selection of more pathogenic hepatitis C virus genotype II during long-term follow-up of interferon-treated patients.

doi:10.1007/BF00189925

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Article

Selection of more pathogenic hepatitis C virus genotype II during long-term follow-up of interferon-treated patients.

Journal of molecular medicine (Berlin, Germany) - 1 May 1995

Villa E, Buttafoco P, Merighi A, Grottola A, Ferretti I, Ferrari A, Callea F, Trande P, Rebecchi A M, Manenti F

Abstract excerpt

The behavior of hepatitis C virus (HCV) infection with regards to type and number of HCV genotypes (tested with genotype-specific nested polymerase chain reaction) was evaluated in 60 patients with anti-HCV-positive chronic active hepatitis without cirrhosis [17 untreated and 43 subjects undergoing single or repeat courses of interferon (IFN) therapy] during a mean follow-up period of 76 +/- 18 months. In...

Topics

Adult
Evaluation Studies as Topic
Female
Follow-Up Studies
Genotype
Hepacivirus
Hepatitis Antibodies
Hepatitis C
Hepatitis C Antibodies
Humans
Interferon alpha-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interferon-alpha

Liver

Liver Cirrhosis

Male

Middle Aged

RNA, Viral

Recombinant Proteins

Source

Open in PubMed

Identifiers

PMID: 7545526
DOI: 10.1007/BF00189925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7545526-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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