Article
Analysis of hepatitis B genotype changes in chronic hepatitis B infection: Influence of antiviral therapy.
Journal of hepatology - 1 Nov 2008
Jardi Rosendo, Rodriguez-Frias Francisco, Schaper Melanie, Giggi Elena, Tabernero David, Homs Maria, Esteban Rafael, Buti Maria
Abstract excerpt
BACKGROUND/AIMS: The frequency of mixed hepatitis B virus (HBV) genotypes in chronic HBV (CHB) and genotype changes during natural disease evolution and as a result of antiviral therapy were investigated. METHODS: Serum samples from 103 CHB patients were included in a cross-sectional study. Longitudinal study of HBV genotypes was performed in 22 patients, 17 of them under antiviral therapy (lamivudine and/or...
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