Article
Interferon therapy in chronic hepatitis C virus: evidence of different outcome with respect to different viral strains.
Journal of medical virology - 1 Apr 1995
Pozzato G, Moretti M, Crocé L S, Sasso F, Kaneko S, Unoura M, Kobayashi K, Crovatto M, Santini G, Tiribelli C
Abstract excerpt
The aim of the study was to assess the role of different viral strains of hepatitis C virus (HCV) in determining the outcome of the alpha-interferon (IFN) therapy. Fifty-seven patients (34 from Italy and 23 from Japan) with HCV-positive liver disease were enrolled in the study. The NS4 region of HCV was amplified in sera by "nested" polymerase chain reaction (PCR) using a primer pair synthesized according to the...
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