Article
Dynamic behavior of hepatitis C virus in chronically infected patients receiving liver graft from infected donors.
Virology - 1 Jun 1996
Laskus T, Wang L F, Rakela J, Vargas H, Pinna A D, Tsamandas A C, Demetris A J, Fung J
Abstract excerpt
We studied the outcome of hepatitis C virus (HCV) infection in 14 patients with end-stage HCV-related liver disease who received HCV-positive liver allografts. Viral sequences specific for donor and recipient were established by direct sequencing of PCR products from the NS5 region and by single-strand conformation polymorphism. Within a few months after transplantation the donor strain took over the recipient...
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