Article
Prevalence of mixed infection by different hepatitis C virus genotypes in patients with hepatitis C virus-related chronic liver disease.
The Journal of laboratory and clinical medicine - 1 Jul 1999
Giannini C, Giannelli F, Monti M, Careccia G, Marrocchi M E, Laffi G, Gentilini P, Zignego A L
Abstract excerpt
Multiple infection by different hepatitis C virus (HCV) genotypes may be of great clinico-pathologic interest. In this study we determined the effective prevalence of coinfections by two or more HCV genotypes in 213 subjects with HCV-positive chronic hepatitis by using genotype-specific polymerase chain reaction (PCR), genotype-specific probe hybridization, and direct sequencing. The most prevalent genotype was...
Topics
- Adult
- Aged
- Base Sequence
- DNA Primers
- Female
- Genotype
- Hepacivirus
- Hepatitis C, Chronic
- Humans
- Italy
- Male
- Middle Aged
- Molecular Sequence Data
- Polymerase Chain Reaction