Article
HnRNP L binds a cis-acting RNA sequence element that enables intron-dependent gene expression.
Genes & development - 15 Jul 1995
Liu X, Mertz J E
Abstract excerpt
Most pre-mRNAs require an intron for efficient processing in higher eukaryotes. To test the hypothesis that intron-independent gene expression involves positive, cis-acting RNA sequence elements, we constructed chimeric genes in which various regions of the naturally intronless HSV-TK gene were i...
Topics
- Animals
- Base Sequence
- Cell Line
- Chimera
- DNA Primers
- DNA, Complementary
- Enhancer Elements, Genetic
- Gene Expression
- Globins
- Heterogeneous-Nuclear Ribonucleoprotein L
- Heterogeneous-Nuclear Ribonucleoproteins
- Humans
