Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HnRNP L binds a cis-acting RNA sequence element that enables intron-dependent gene expression.

Genes & development - 15 Jul 1995

Liu X, Mertz J E

Abstract excerpt

Most pre-mRNAs require an intron for efficient processing in higher eukaryotes. To test the hypothesis that intron-independent gene expression involves positive, cis-acting RNA sequence elements, we constructed chimeric genes in which various regions of the naturally intronless HSV-TK gene were inserted into an intronless variant of the highly intron-dependent human beta-globin gene. Using a transient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression
Share to Base Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Complementary

Share to DNA Primers

Share to Introns

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 7542615
DOI: 10.1101/gad.9.14.1766

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HnRNP L binds a cis-acting RNA sequence element that enables intron-dependent gene expression.PMID 7542615Read ↗

Binding of hnRNP L to the Pre-mRNA Processing Enhancer of the Herpes Simplex Virus Thymidine Kinase Gene Enhances both Polyadenylation and Nucleocytoplasmic Export of Intronless mRNAsSemantic proximity Read ↗

The human cytomegalovirus regulatory protein UL69 and its effect on mRNA exportSemantic proximity Read ↗

Heterogeneous nuclear ribonucleoprotein H is required for optimal U11 small nuclear ribonucleoprotein binding to a retroviral RNA-processing control element: implications for U12-dependent RNA splicing.Semantic proximity Read ↗

A novel type of splicing enhancer regulating adenovirus pre-mRNA splicing.Semantic proximity Read ↗

Identification of an hnRNP A1-Dependent Splicing Silencer in the Human Papillomavirus Type 16 L1 Coding Region That Prevents Premature Expression of the Late L1 GeneSemantic proximity Read ↗

Nuclear degradation of nonsense mutated beta-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of beta-thalassemia?Semantic proximity Read ↗

Synergistic stimulation of HIV-1 rev-dependent export of unspliced mRNA to the cytoplasm by hnRNP A1.Semantic proximity Read ↗

An in vitro system for expression analysis of mutations of the beta-globin gene: validation and application to two mutations in the 5' UTR.Semantic proximity Read ↗

A nucleolin-binding 3' untranslated region element stabilizes beta-globin mRNA in vivo.Semantic proximity Read ↗

Mutation of an RSV intronic element abolishes both U11/U12 snRNP binding and negative regulation of splicing.Semantic proximity Read ↗

Role of the Hepatitis B Virus Posttranscriptional Regulatory Element in Export of Intronless TranscriptsSemantic proximity Read ↗

The neuron-specific RNA-binding protein ELAV regulates neuroglian alternative splicing in neurons and binds directly to its pre-mRNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.