Article
Analysis of hematopoietic stem and progenitor cell populations in cytomegalovirus-infected mice.
Blood - 15 Jul 1995
Gibbons A E, Price P, Shellam G R
Abstract excerpt
We have studied the effects of murine cytomegalovirus (MCMV) infection on bone marrow stem and progenitor cell populations to find an explanation for the defects in hematopoiesis that accompany CMV infections in patients. Sublethal MCMV infection of BALB/c mice resulted in a 5- to 10-fold decrease in the numbers of myeloid (colony-forming unit-granulocyte-macrophage [CFU-GM]) and erythroid (burst-forming...
Topics
- Animals
- Antigens, Ly
- Biomarkers
- Bone Marrow
- Bone Marrow Transplantation
- Cell Count
- Cells, Cultured
- Colony-Forming Units Assay
- Cytomegalovirus Infections
- Female
- Genetic Predisposition to Disease
