Article
Cytomegalovirus mediated myelosuppression.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2002
Randolph-Habecker Julie, Iwata Mineo, Torok-Storb Beverly
Abstract excerpt
Cytomegalovirus (CMV) has long been associated with myelosuppression. Evidence for this association has been provided from in vitro studies, statistical analysis of clinical studies, informative case reports, and murine models. Reports differ as to how CMV mediates myelosuppression. Some data indicate direct infection of hematopoietic progenitors and their progeny, others indicate that the supportive...
Topics
- Animals
- Bone Marrow Cells
- Cells, Cultured
- Cytomegalovirus
- Cytomegalovirus Infections
- Female
- Fibroblasts
- Genetic Variation
- Hematopoiesis
- Hematopoietic Stem Cells
- Humans