Article
HLA-DRB1 alleles associated with rheumatoid arthritis in southern France. Absence of extraarticular disease despite expression of the shared epitope.
The Journal of rheumatology - 1 Apr 1995
Benazet J F, Reviron D, Mercier P, Roux H, Roudier J
Abstract excerpt
OBJECTIVE: Extraarticular rheumatoid arthritis (RA) is almost unknown in Marseille in southern France. We investigated whether this was due to rare expression of the HLA-DRB1 shared epitope. METHODS: HLA-DRB1 alleles were characterized in 73 patients with RA and 108 controls by polymerase chain reaction amplification and oligonucleotide hybridization. RESULTS: In patients with RA, 76% expressed the shared epitope...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
