Article
HLA-DRB1 alleles associated with rheumatoid arthritis in southern France. Absence of extraarticular disease despite expression of the shared epitope.
The Journal of rheumatology - 1 Apr 1995
Benazet J F, Reviron D, Mercier P, Roux H, Roudier J
Abstract excerpt
OBJECTIVE: Extraarticular rheumatoid arthritis (RA) is almost unknown in Marseille in southern France. We investigated whether this was due to rare expression of the HLA-DRB1 shared epitope. METHODS: HLA-DRB1 alleles were characterized in 73 patients with RA and 108 controls by polymerase chain r...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Arthritis, Rheumatoid
- Epitopes
- Female
- France
- Genotype
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Male
- Mediterranean Sea
- Middle Aged
- Risk Factors
