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Article

Study of the frequency of HLA-DRB1 alleles in Brazilian patients with rheumatoid arthritis.

Revista brasileira de reumatologia - 1 Jan 2000

Usnayo Magali Justina Gómez, Andrade Luis Eduardo Coelho, Alarcon Renata Triguenho, Oliveira Juliana Cardoso, Silva Gustavo Milson Fabrício, Bendet Izidro, Burlingame Rufus, Porto Luis Cristóvão, Pinheiro Geraldo da Rocha Castelar

Abstract excerpt

UNLABELLED: The HLA-DRB1 alleles encoding an amino acid sequence (QKRAA/QRRAA/RRRAA) at position 70 74 of the third hypervariable region of the β1 chain of the HLA-DRB1 gene, called shared epitope (SE), are associated with increased susceptibility to and severity of rheumatoid arthritis (RA) in different populations. OBJECTIVE: To determine the frequency of HLA-DRB1 alleles in Brazilian patients with RA and their...

Topics

Adolescent
Adult
Alleles
Arthritis, Rheumatoid
Brazil
Case-Control Studies
Female
HLA-DRB1 Chains
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Young Adult

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PMID: 21952999

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ACR

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