Localized Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1.

doi:10.1002/j.1460-2075.1995.tb07196.x

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Article

Localized Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1.

The EMBO journal - 1 May 1995

Mahone M, Saffman E E, Lasko P F

Abstract excerpt

The Bicaudal-C (Bic-C) gene of Drosophila melanogaster is required for correct targeting of the migrating anterior follicle cells and for specifying anterior position. Females lacking any wild type copies of Bic-C produce only eggshells open at the anterior end, because of the failure of the columnar follicle cells to migrate in the correct position at the nurse cell--oocyte boundary. Embryos which develop from...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
DNA
Drosophila Proteins
Drosophila melanogaster
Female
Fragile X Mental Retardation Protein
Genes, Insect
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insect Hormones

Male

Molecular Sequence Data

Nerve Tissue Proteins

Oocytes

Phenotype

RNA

Source

Open in PubMed Open full text

Identifiers

PMID: 7538070
DOI: 10.1002/j.1460-2075.1995.tb07196.x
PMCID: PMC398304

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7538070-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Localized Bicaudal-C RNA encodes a protein containing a KH domain, the RNA binding motif of FMR1.PMID 7538070Read ↗

Premature translation of oskar in oocytes lacking the RNA-binding protein bicaudal-C.Semantic proximity Read ↗

Anterior-posterior axis specification in Drosophila oocytes: identification of novel bicoid and oskar mRNA localization factors.Semantic proximity Read ↗

Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression.Semantic proximity Read ↗

Bicaudal-C associates with a Trailer Hitch/Me31B complex and is required for efficient Gurken secretion.Semantic proximity Read ↗

The receptor-like tyrosine phosphatase lar is required for epithelial planar polarity and for axis determination within drosophila ovarian follicles.Semantic proximity Read ↗

spoonbill, a new Drosophila female-sterile mutation, interferes with chromosome organization and dorsal-ventral patterning of the egg.Semantic proximity Read ↗

maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.Semantic proximity Read ↗

Microtubule-actin crosslinking factor 1 (Macf1) domain function in Balbiani body dissociation and nuclear positioningSemantic proximity Read ↗

Drosophila rhino encodes a female-specific chromo-domain protein that affects chromosome structure and egg polarity.Semantic proximity Read ↗

Bicaudal C and trailer hitch have similar roles in gurken mRNA localization and cytoskeletal organization.Semantic proximity Read ↗

fusilli, an essential gene with a maternal role in Drosophila embryonic dorsal-ventral patterning.Semantic proximity Read ↗

Par-1 regulates bicoid mRNA localisation by phosphorylating Exuperantia.Semantic proximity Read ↗

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