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Article

Identification of amino acids important for binding of Clostridium perfringens epsilon toxin to host cells and to HAVCR1.

Biochemistry - 25 Sept 2012

Ivie Susan E, McClain Mark S

Abstract excerpt

Clostridium perfringens epsilon toxin belongs to the aerolysin-like family of pore-forming toxins and is one of the most potent bacterial toxins known. The epsilon toxin causes fatal enterotoxemia in sheep, goats, and possibly humans. Evidence indicates that the toxin binds to protein receptors including hepatitis A virus cellular receptor 1 (HAVCR1), but the region of the toxin responsible for cell binding has...

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Source

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Identifiers

PMID: 22938730
DOI: 10.1021/bi300690a
PMCID: PMC3534817

Genes

HAVCR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of amino acids important for binding of Clostridium perfringens epsilon toxin to host cells and to HAVCR1.PMID 22938730Read ↗

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