Article
Analysis of linkage disequilibrium between different cystic fibrosis mutations and three intragenic microsatellites in the Italian population.
Human mutation - 1 Jan 1995
Russo M P, Romeo G, Devoto M, Barbujani G, Cabrini G, Giunta A, D'Alcamo E, Leoni G, Sangiuolo F, Magnani C
Abstract excerpt
Three intragenic microsatellites of the CFTR gene, a TA and a CA repeats, namely IVS17bTA and IVS17bCA, located in intron 17b and a CA repeat (IVS8CA) located in intron 8 of the CFTR gene, were analyzed in a large sample of Italian cystic fibrosis (CF) and normal chromosomes. Linkage disequilibri...
Topics
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- DNA, Satellite
- Genetics, Population
- Haplotypes
- Humans
- Italy
- Linkage Disequilibrium
- Membrane Proteins
- Models, Genetic
- Mutation
- Oligodeoxyribonucleotides
- Repetitive Sequences, Nucleic Acid