Article
Detection of hydroquinone-induced nonrandom breakage in the centromeric heterochromatin of mouse bone marrow cells using multicolor fluorescence in situ hybridization with the mouse major and minor satellite probes.
Mutagenesis - 1 Nov 1994
Chen H W, Tomar R, Eastmond D A
Abstract excerpt
Fluorescence in situ hybridization with a mouse major satellite probe and CREST staining were used to characterize the origin of micronuclei occurring in mouse bone marrow erythrocytes following administration of the benzene metabolite hydroquinone. Hydroquinone was administered to male CD-1 mice...
Topics
- Animals
- Base Sequence
- Bone Marrow Cells
- Cells, Cultured
- Centromere
- DNA Probes
- Heterochromatin
- Hydroquinones
- In Situ Hybridization, Fluorescence
- Male
- Mice
- Mice, Inbred Strains
- Micronucleus Tests
- Molecular Sequence Data
- Mutagens
- Mutation
- Staining and Labeling