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Article

PI3K signaling and miRNA expression during the response of quiescent human fibroblasts to distinct proliferative stimuli

31 May 2006

Abstract excerpt

BACKGROUND: Serum treatment of quiescent human dermal fibroblasts induces proliferation, coupled with a complex physiological response that is indicative of their normal role in wound-healing. However, it is not known to what extent such complex transcriptional events are specific to a given cell type and signal, and how these global changes are coordinately regulated. We have profiled the global transcriptional...

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PMID: 16737555
DOI: 10.1186/gb-2006-7-5-r42

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