[Possibilities of using Salmonella cya, crp mutants as vectors of an oral recombinant vaccine].

Article

[Possibilities of using Salmonella cya, crp mutants as vectors of an oral recombinant vaccine].

Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 1994

Boĭchenko M N, Vorob'ev A A, Gusev V V, Tymchuk S N

Abstract excerpt

The Salmonella typhimurium B-2/1 double mutant with cya and crp mutations was obtained by a recombination process. The mutant exhibited a low virulence and inability to utilize citrate. In terms of these properties, the mutant differs from the wild-type strain. The mutant is able to persist in th...

Topics

Administration, Oral
Animals
Bacterial Vaccines
Cattle
Mice
Mutation
Papio
Salmonella typhimurium
Vaccines, Synthetic
Virulence

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