Article
The influence of large deletions on the mutation frequency induced by tritiated water and X-radiation in male Drosophila melanogaster post-meiotic germ cells.
Mutation research - 1 May 1994
Fossett N G, Byrne B J, Kelley S J, Tucker A B, Arbour-Reily P, Lee W R
Abstract excerpt
Tritium beta radiation (3H beta-radiation) in the form of tritiated water was used to induce mutations at the alcohol dehydrogenase (Adh) locus in male Drosophila melanogaster post-meiotic germ cells. All 23 Adh null mutations were large deletions (> 20 kb), determined by genetic complementation and Southern blot analyses. 27 Adh null mutations have been induced by 100-kVp X-rays (Aaron, 1979) and have been...
Topics
- Alcohol Dehydrogenase
- Animals
- Beta Particles
- Drosophila melanogaster
- Genetic Complementation Test
- Male
- Mutation
- Sequence Deletion
- Spermatozoa
- Tritium
- Water