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Article

TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells

14 Apr 2006

Abstract excerpt

The relevance of the diversity of endothelial cells (ECs) for the response to inflammatory stimuli is currently not well defined. Using oligonucleotide microarray technique, we systematically analyzed the tumor necrosis factor (TNF)-induced expression profile in human microvascular ECs (HMEC) and macrovascular human umbilical vein ECs (HUVEC), analyzing 13,000 human genes by microarray analysis. Using strict...

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PMID: 16617158
DOI: 10.1189/jlb.0905530

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