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Article

Additive effects of steel factor and antisense TGF-beta 1 oligodeoxynucleotide on CD34+ hematopoietic progenitor cells.

Leukemia - 1 Mar 1994

Li M L, Cardoso A A, Sansilvestri P, Hatzfeld A, Brown E L, Sookdeo H, Levesque J P, Clark S C, Hatzfeld J

Abstract excerpt

We previously demonstrated that TGF-beta 1 antisense oligodeoxynucleotides can release early CD34+ bone marrow progenitors from quiescence, and increase the numbers of mixed and large erythroid colonies. As Steel Factor (SF) has a similar effect on colony formation by CD34+ cells, we tested wheth...

Topics

Antigens, CD
Antigens, CD34
Drug Synergism
Fetal Blood
Hematopoietic Cell Growth Factors
Hematopoietic Stem Cells
Humans
Oligonucleotides, Antisense
Phenotype
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-kit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptor Protein-Tyrosine Kinases

Receptors, Colony-Stimulating Factor

Stem Cell Factor

Transforming Growth Factor beta

Source

Identifiers

PMID: 7510356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7510356-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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