Article
Origin of stroma cells in long-term bone marrow cultures from patients with acute myeloid leukemia.
Annals of hematology - 1 Jul 1999
Zhang W, Knieling G, Vohwinkel G, Martinez T, Kuse R, Hossfeld D K, Dührsen U
Abstract excerpt
Bone marrow stroma cells from patients with acute myeloid leukemia (AML) display a variety of functional abnormalities. In order to determine whether this is related to an imbalance in the proportion of different stroma cell types or to integration of leukemic progeny into the regulatory cell network, stroma layers were established in mycophenolic acid-treated long-term marrow cultures from 16 patients with AML...
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