Article
Sequence conservation within neutralization epitope regions of VP7 and VP4 proteins of human serotype G4 rotavirus isolates.
Archives of virology - 1 Jan 1993
Palombo E A, Bishop R F, Cotton R G
Abstract excerpt
Serotype G4 rotavirus isolates causing four separate epidemics of severe diarrhoea in young children in Melbourne, Australia (from 1974-1990) were investigated for sequence variation in genes encoding the outer capsid proteins, VP4 and VP7. Complementary DNA of the gene encoding the major outer capsid neutralization antigen, VP7, of eighteen isolates was synthesized and amplified by coupled reverse transcription...
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