Article
Intra- and inter-season genetic variability in the VP7 gene of serotype 1 (monotype 1 a) rotavirus clinical isolates.
Archives of virology - 1 Jan 1993
Palombo E A, Bishop R F, Cotton R G
Abstract excerpt
Nucleotide sequence variation was detected in the VP7 gene of serotype 1 (monotype 1 a) rotavirus isolates collected from children admitted to hospital in Melbourne with acute diarrhoea in 1990 and 1991. Two co-circulating electropherotypes were detected during the 1991 winter epidemic. Using chemical cleavage of mismatches in heteroduplexes, the genes encoding VP7 were found to be genetically stable within each...
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