Article
The irregular chiasm C-roughest locus of Drosophila, which affects axonal projections and programmed cell death, encodes a novel immunoglobulin-like protein.
Genes & development - 1 Dec 1993
Ramos R G, Igloi G L, Lichte B, Baumann U, Maier D, Schneider T, Brandstätter J H, Fröhlich A, Fischbach K F
Abstract excerpt
The axonal projection mutations irregular chiasm C of Drosophila melanogaster comap and genetically interact with the roughest locus, which is required for programmed cell death in the developing retina. We cloned the genomic region in 3C5 by transposon tagging and identified a single transcription unit that produces a major, spatially and temporally regulated mRNA species of approximately 5.0 kb. Postembryonic...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Apoptosis
- Axons
- Base Sequence
- Cell Adhesion Molecules, Neuronal
- Drosophila Proteins
- Drosophila melanogaster
- Eye Proteins