Article
Ubiquitous overexpression of a transgene encoding the extracellular portion of the Drosophila roughest-irregular chiasm C protein induces early embryonic lethality.
Anais da Academia Brasileira de Ciencias - 1 Sept 2000
Moda L, Machado R C, Ramos R G
Abstract excerpt
The cell adhesion molecule Rst-irreC is a transmembrane glycoprotein of the immunoglobulin superfamily involved in several important developmental processes in Drosophila, including axonal pathfinding in the optic lobe and programmed cell death and pigment cell differentiation in the pupal retina. As an initial step towards the "in vivo" functional analysis of this protein we have generated transgenic fly stocks...
Topics
- Animals
- Cell Adhesion Molecules, Neuronal
- Drosophila Proteins
- Drosophila melanogaster
- Embryo, Nonmammalian
- Eye Proteins
- Female
- Gene Expression Regulation, Developmental
- Genes, Insect
- Genes, Lethal
- Hot Temperature
- Insect Proteins
- Male
- Phenotype
- Shock
- Transgenes