Article
Phenotypic characterization of circulating antibody-secreting cells after mucosal and systemic immunizations in humans.
Advances in experimental medicine and biology - 1 Jan 1995
Lakew M, Nordström I, Quiding M, Holmgren J, Butcher E, Czerkinsky C
Abstract excerpt
We have developed a simple approach for immunophenotyping of functional lymphoid cell subpopulations. Using this approach we have partly characterized circulating antigen-specific ASC after systemic versus mucosal immunization with respect to maturational and activation stages, and to their anatomic commitment(s). Comparative analyses of mucosally versus systemically activated circulating ASC reveal differences...
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