Article
Detection of oxidative mutagens in strains of Escherichia coli deficient in the OxyR or MutY functions: dependence on SOS mutagenesis.
Mutation research - 1 Nov 1995
Urios A, Herrera G, Blanco M
Abstract excerpt
The Escherichia coli strain IC3821, a delta oxyR derivative of WP2 uvrA trpE65, was more sensitive to mutagenicity promoted by t-butyl hydroperoxide and cumene hydroperoxide than the isogenic oxyR+ control. Mutagenicity of menadione, a redox cycling quinone, was clearly detected in the delta oxyR strain, whereas only a slight mutagenic response was observed in the oxyR+ strain. Plumbagin, another quinone...
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