Viral mutations, TCR antagonism and escape from the immune response.

Abstract excerpt

Persistent viruses use several mechanisms to evade the immune response, including the generation of mutations that affect TCR recognition. It has recently been reported that spontaneous mutations at TCR contact sites within individual viral epitopes in certain persistent human viruses can abrogat...

Topics

• Humans
• Mutation
• Receptors, Antigen, T-Cell
• Virus Diseases