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Cellular factors required for papillomavirus DNA replication

1 Dec 1995

Abstract excerpt

In vitro replication of papillomavirus DNA has been carried out with a combination of purified proteins and partially purified extracts made from human cells. DNA synthesis requires the viral E1 protein and the papillomavirus origin of replication. The E2 protein stimulates DNA synthesis in a binding site-independent manner. Papillomavirus DNA replication is also dependent on the cellular factors replication...

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PMID: 7494298
DOI: 10.1128/jvi.69.12.7857-7867.1995

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