Article
Immunogenicity of intraperitoneal insulin infusion using programmable implantable devices.
Diabetologia - 1 May 1995
Jeandidier N, Boivin S, Sapin R, Rosart-Ortega F, Uring-Lambert B, Réville P, Pinget M
Abstract excerpt
Intraperitoneal insulin infusion using implantable devices in insulin-dependent diabetic (IDDM) patients is promising since it improves diabetic control and decreases frequency of hypoglycaemia. However, preliminary data show a striking increase in plasma levels of anti-insulin antibodies with th...
Topics
- Adult
- Alleles
- Blood Glucose
- Complement C4
- Diabetes Mellitus, Type 1
- Female
- Follow-Up Studies
- Glycated Hemoglobin
- Histocompatibility Testing
- Humans
- Hypoglycemia
- Infusions, Parenteral
- Insulin
- Insulin Antibodies
- Insulin Infusion Systems
- Male
- Peritoneal Cavity
- Recombinant Proteins