Article
Immunization of mice by oral colonization with live recombinant commensal streptococci.
Vaccine - 1 Jan 1995
Oggioni M R, Manganelli R, Contorni M, Tommasino M, Pozzi G
Abstract excerpt
To test the use of recombinant streptococci as live vaccine vectors, colonization/immunization experiments were performed with Streptococcus gordonii expressing heterologous cell-surface antigens. Three isogenic strains of S. gordonii were used: a wild-type, a recombinant expressing the M6 protein of Streptococcus pyogenes, and a recombinant expressing the E7 protein of human papillomavirus type 16 as a fusion...
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