Article
Immunization of mice by oral colonization with live recombinant commensal streptococci.
Vaccine - 1 Jan 1995
Oggioni M R, Manganelli R, Contorni M, Tommasino M, Pozzi G
Abstract excerpt
To test the use of recombinant streptococci as live vaccine vectors, colonization/immunization experiments were performed with Streptococcus gordonii expressing heterologous cell-surface antigens. Three isogenic strains of S. gordonii were used: a wild-type, a recombinant expressing the M6 protei...
Topics
- Administration, Oral
- Animals
- Antibodies, Bacterial
- Bacterial Vaccines
- Female
- Mice
- Mouth Mucosa
- Pharynx
- Phenotype
- Streptococcus sanguis
- Vaccines, Synthetic