Article
Vaccination equally enables both genetically susceptible and resistant mice to control infection with group A streptococci.
Microbes and infection - 1 Feb 2006
Siegert Jeannette, Sastalla Inka, Chhatwal Gursharan Singh, Medina Eva
Abstract excerpt
There is substantial evidence that host genetic factors are important in determining susceptibility to infection with group A streptococci (GAS). Several studies have revealed that, similarly to humans, a genetic component may be important in determining susceptibility to GAS infection in mice. Thus, C3H/HeN mice are much more susceptible to streptococcal infection than BALB/c mice. We have determined here...
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