Article
[Lewis-x, a sugar chain structure, suppresses the epileptic seizure in El mouse].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica - 1 Jan 1995
Masuda Y
Abstract excerpt
El mouse is a mutant strain with genetic epileptogenicity. Epileptic convulsion of El mouse has been shown to be related to metabolical and structural abnormalities in the hippocampal neuron. Gamma-globulin purified from the human serum has a marked anti-convulsive effect in El mouse. Human IgG, 80% of the gamma-globulin, has the reactivity indicating the presence of Lewis-x structure in the sugar chain. In the...
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