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Article

The bugeye mutant zebrafish exhibits visual deficits that arise with the onset of an enlarged eye phenotype.

Investigative ophthalmology & visual science - 13 Jun 2011

Stujenske Joseph M, Dowling John E, Emran Farida

Abstract excerpt

PURPOSE: The bugeye mutant has an enlarged eye phenotype, presumably because of elevated intraocular pressure. Since elevated intraocular pressure is a significant risk factor for glaucoma, the bugeye zebrafish mutant may be a model organism for the disease. METHODS: The optomotor response (OMR) was used to assess visual responsiveness in both larval and adult zebrafish. Electroretinograms (ERGs) were recorded to...

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Identifiers

PMID: 21460263
DOI: 10.1167/iovs.10-6434
PMCID: PMC3175981

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ERG

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Source receipt: pubmed, retrieved 7 Sept 2026.

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