Article
The number of segregating sites in expanding human populations, with implications for estimates of demographic parameters.
Molecular biology and evolution - 1 Sept 1995
Bertorelle G, Slatkin M
Abstract excerpt
The frequency distribution of pairwise differences between sequences of mtDNA has recently been used to estimate the size of human populations before and after a hypothetical episode of rapid population growth and the time at which the population grew. To test the internal consistency of this method, we used three different sets of human mtDNA data and the corresponding demographic parameters estimated from the...
Topics
- Animals
- DNA, Mitochondrial
- Demography
- Hominidae
- Humans
- Italy
- Middle East
- Models, Genetic
- Models, Statistical
- Mutation
- Poisson Distribution
- Population Growth