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Article

The impact of population expansion and mutation rate heterogeneity on DNA sequence polymorphism.

Molecular biology and evolution - 1 Mar 1996

Aris-Brosou S, Excoffier L

Abstract excerpt

In order to study the effect of mutation rate heterogeneity on patterns of DNA polymorphism, we simulated samples of DNA sequences with gamma-distributed nucleotide substitution rates in stationary and expanding populations. We find that recent population expansions and mutation rate heterogeneity have similar effects on several polymorphism indicators, like the shape and the mean of the observed pairwise...

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PMID: 8742638
DOI: 10.1093/oxfordjournals.molbev.a025610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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