Article
Assessment of the ability of 4CMB and 4HMB to induce primary genetic damage in strains of Escherichia coli.
Mutation research - 1 Jan 2000
May K, Lodge D C, Bootman J
Abstract excerpt
Studies were undertaken to investigate the ability of 4CMB and 4HMB to induce primary DNA damage in bacteria as shown by differential lethality in strains of E. coli proficient and deficient in DNA repair. It has been demonstrated in these laboratories that the assay system used will detect weak DNA-damaging agents by the use of a prolonged incubation period and, where appropriate, the inclusion of an S9 mix...
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