Article
The induction of mitotic gene conversion in the yeast, Saccharomyces cerevisiae JD1 by 4-chloromethylbiphenyl (4CMB), benzyl chloride (BC) and 4-hydroxymethylbiphenyl (4HMB).
Mutation research - 1 Jan 2000
Brooks T M, Gonzalez L P
Abstract excerpt
The induction of mitotic gene conversion by 4CMB, BC and 4HMB was studied in both log-phase and stationary-phase cultures of the yeast, Saccharomyces cerevisiae JD1. Assays were performed both in the presence and in the absence of S9 microsomal fraction obtained from a liver homogenate from rats...
Topics
- Animals
- Benzyl Compounds
- Biotransformation
- Biphenyl Compounds
- Gene Conversion
- Microsomes, Liver
- Mitosis
- Mutagenicity Tests
- Mutagens
- Mutation
- Rats
- Saccharomyces cerevisiae